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U 89843A

CAS No. 157013-32-6

U 89843A ( —— )

产品货号. M27731 CAS No. 157013-32-6

U 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥7857 有现货
50MG ¥16038 有现货
100MG ¥20250 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    U 89843A
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    U 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors.
  • 产品描述
    U 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors.(In Vitro):In the alpha 1 beta 2 gamma 2 subtype of GABAA receptors expressed in human embryonic kidney cells, U 89843A dose-dependently enhanced 5 microM GABA-induced Cl- currents with a maximal enhancement of 362 +/- 91%, a half-maximal concentration of 2 +/- 0.4 microM and a slope factor of 1.1 +/- 0.4. U 89843A also inhibited [35S]t-butylbicyclophosphorothionate binding in rat cerebrocortical membranes with a similar half-maximal inhibitory concentration.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    acetylcholinesterase
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    157013-32-6
  • 分子量
    321.9
  • 分子式
    C16H24ClN5
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    Cl.Cc1cc2c(nc(nc2n1C)N1CCCC1)N1CCCC1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Dafforn A, et al. Acetylcholinesterase inhibition by the ketone transition state analog phenoxyacetone and 1-halo-3-phenoxy-2-propanones. Biochem Biophys Res Commun. 1982 Jan 29;104(2):597-602.
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